RecruitingNCT04103281

Expression Profiles of Integrin αDβ2 on Neutrophils in Sepsis


Sponsor

Boston Children's Hospital

Enrollment

75 participants

Start Date

Sep 1, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

In this research study we want to learn more about the characteristics of neutrophils that are present in the blood and secretions from a breathing tube of patients with sepsis. Sepsis is a severe type of infection, affecting various parts of the body. Neutrophils are a type of white blood cell that are part of the body's immune system. Even though neutrophils are important in getting rid of germs, they also may be harmful to parts of the body by causing injury in the lungs in patients with sepsis. Neutrophils can change their character in sepsis. Because of this, it is important for doctors to know what kind of neutrophils are in the blood and secretions from the breathing tube of patients with sepsis so that they can work to develop therapies to prevent these cells from being harmful.


Eligibility

Min Age: 2 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Sepsis for people with sepsis. The study is currently recruiting participants at 1 location. People eligible for this study include aged 2 Years to 50 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSepsis

Sepsis patients in the ICU with a breathing tube


Locations(1)

Boston Children's Hospital

Boston, Massachusetts, United States

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NCT04103281


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