Phase I/II Clinical Study to Evaluate VB15010 Tablets in Patients With Advanced Solid Tumors

This early-phase study tests the safety and best dose of an investigational drug called VB15010 in patients with advanced solid tumors that have a specific type of DNA repair gene mutation (called homologous recombination repair mutation), such as BRCA mutations. **You may be eligible if...** - You are 18 or older - You have an advanced cancer confirmed by biopsy or lab test - Your cancer is actively growing/progressing - Your cancer has a homologous recombination repair gene mutation (e.g., BRCA1/2) - Your organs (kidney, liver, bone marrow) are functioning adequately **You may NOT be eligible if...** - You had major surgery within 4 weeks of starting treatment - You have active or unstable brain metastases requiring steroids - You have a history of a blood cancer precursor condition (MDS/AML) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.