RecruitingNCT06822504

Prevalence of Sarcopenic Obesity in COPD

ESPEN-EASO Sarcopenic Obesity (OS) Diagnostic Criteria Application in a COPD Cohort and OS Correlation to Diaphragmatic Thickness and Mobility for Determination of Tailored Pulmonary Rehabilitation Program: an Observational Study

Sponsor

IRCCS San Raffaele Roma

Enrollment

236 participants

Start Date

Jun 1, 2024

Study Type

OBSERVATIONAL

Conditions

COPD Sarcopenic Obesity

Summary

The goal of this observational study is to the purpose is to apply of ESPEN/EASO criteria for the diagnosis of sarcopenic obesity and calculation of OS prevalence in a sample of COPD patients. In addition, this study want to evaluate the impact of sarcopenic obesity on the respiratory function of COPD patients and the degree of severity of respiratory disease, assessed by spirometric examination; diaphragm thickness and excursion, by ultrasonographic study; performance, assessed by six-minute walk test (6-MWT); quality of life and degree of dyspnea (mMRC, Barthel dyspnea, S. George Respiratory Questionnaire); compliance and outcomes at the end of the respiratory rehabilitation course. Comparison with normal-weight patients with and without sarcopenia will help to better understand the clinical impact of sarcopenic obesity in this category of patients.

Eligibility

Min Age: 40 YearsMax Age: 100 Years

Plain Language Summary

Simplified for easier understanding

This observational study measures how common sarcopenic obesity (a combination of muscle loss and excess body fat) is in patients with stable COPD (chronic obstructive pulmonary disease, a lung condition), and how it affects their health and exercise ability. **You may be eligible if...** - You are over 40 years old (male or female) - You have a confirmed stable COPD diagnosis (per GOLD guidelines) - Your BMI is 18.5 or above **You may NOT be eligible if...** - Your COPD is currently in a flare-up or unstable - Your BMI is below 18.5 - You have a tracheostomy - You have uncontrolled high blood pressure or low blood pressure - You have significant other conditions that limit your ability to exercise - You have an active infection (including HIV) - You have been diagnosed with a malignancy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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