RecruitingNot ApplicableNCT06823570

Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension.

Anti-hypertensive Therapy and Exercise Treatment to Improve Vascular Health in Patients With Hypertension. A Randomized Controlled Trial.

Sponsor

Heinrich-Heine University, Duesseldorf

Enrollment

60 participants

Start Date

Apr 1, 2025

Study Type

INTERVENTIONAL

Conditions

Hypertension Vascular Function Fitness Testing Metabolism Changes

Summary

This is a prospective, monocentric, randomized controlled trial to investigate the effect of anti-hypertensive treatment and/or individualized exercise training intervention on blood pressure and vascular health. Furthermore the investigators want to decipher mechanisms, which contribute to vascular health by analyzing changes in metabolism and cell function in relation to vascular reaction.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether treating high blood pressure with medication combined with an exercise program can improve thinking and memory (cognitive function) in older adults, especially those at risk of cognitive decline. **You may be eligible if...** - You are an older adult (likely 60 or older) with high blood pressure - You have some mild concerns about your memory or thinking - You are not currently exercising regularly - You are able to participate in a supervised exercise program **You may NOT be eligible if...** - You have already been diagnosed with dementia - You have serious heart or lung conditions that prevent exercise - Your blood pressure is already well-controlled - You have had a recent stroke or heart attack - You are unable to complete cognitive tests Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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