Evaluation of RBS2418 in Patients With Advanced, Metastatic, and Progressive Colorectal Cancer

This study is testing RBS2418, an experimental drug, in people with advanced or metastatic urothelial carcinoma (bladder cancer) and potentially other solid tumors that have not responded to standard treatments. **You may be eligible if...** - You are 18 or older - You have advanced or metastatic urothelial carcinoma (or another qualifying solid tumor) - You have received prior standard treatments (including platinum-based chemotherapy and/or immunotherapy) - You are in reasonably good physical condition (ECOG score 0–1) - Your organ function is within acceptable ranges **You may NOT be eligible if...** - You have untreated or active brain metastases - You have active autoimmune disease - You are on chronic immunosuppressive therapy - You are pregnant or breastfeeding - You have had recent major surgery or serious active infections Talk to your doctor to see if this trial is right for you.