RecruitingNot ApplicableNCT06824415

Sleep TMS for Depression

Optimizing Depression Treatment Through Sleep-state Brain Stimulation


Sponsor

Stanford University

Enrollment

15 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to establish the feasibility, tolerability, and preliminary efficacy of sleep-state transcranial magnetic stimulation (TMS) for enhancing plasticity in depression treatment.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Inclusion Criteria3

  • Current Major Depressive Disorder (MDD) diagnosis
  • Failed >= 1 antidepressant medication
  • Moderate-to-severe depression

Exclusion Criteria5

  • Intellectual disability
  • Significant head injury/neurological disorder
  • Pregnancy or postpartum
  • TMS/MRI contraindications
  • Active substance use/suicidal ideation

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Interventions

DEVICETMS

Transcranial magnetic stimulation (TMS) applies magnetic pulses to stimulate nerve cells in the brain.


Locations(1)

Stanford University

Stanford, California, United States

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NCT06824415


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