RecruitingNot ApplicableNCT06825520

Investigating Changes in Premonitory Urges During Habit Reversal Training for Tics

Investigating Changes in Premonitory Urges During Habit Reversal Training

Sponsor

University of Utah

Enrollment

6 participants

Start Date

Feb 11, 2025

Study Type

INTERVENTIONAL

Conditions

Tourette Syndrome in Children Tourette Syndrome in Adolescence Tics Tourette Disorder

Summary

The primary aim of this study is to learn more about premonitory urges (PU) when using Habit Reversal Training (HRT) to treat tics. The main focus of this study is to investigate if and when PU change during tic treatment sessions and between tic treatment sessions. Participants will: * Attend 5 study visits (approximately 1 to 1.5 hours each) for an intake, habit reversal training for 3 separate tics, and a post assessment * Attend 5 practice sessions (approximately 30 minutes each) over a week for 3 weeks (total 15 practice sessions) * Study visits and practice sessions will take place in person and online via secure videoconference

Eligibility

Min Age: 8 YearsMax Age: 17 Years

Inclusion Criteria6

Participants who meet criteria for a DSM-5-TR diagnosis of a TD will be recruited to participate in this study. Participants will be eligible for the study if they
present with at least three motor and/or vocal tics and are interested in receiving treatment,
report experiencing a PU for each of their target tics with a minimum rating of a 4/8 on a subjective rating (i.e., the Urge Thermometer; Silverman \& Albano, 1996) for each tic,
the targeted tics occur, on average, at least once per minute during a 10-minute direct observation,
are between the ages of 8 and 17
the patient has no planned changes in medication initiation or dosage during their study participation period.

Exclusion Criteria4

the presence of any comorbid conditions that are considered a primary treatment concern and/or could interfere with study participation or treatment (i.e., unmanaged ADHD, OCD, anxiety),
have previously engaged in CBIT or HRT for more than 2 sessions,
a Yale Global Tic Severity Score of 40+ (or 20+ if they present with a primary motor or vocal tic disorder),
suspected (based on clinical presentation) that the tics are better attributed to functional neurological symptom disorder per DSM-5-TR criteria (APA, 2022).

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Interventions

BEHAVIORALHabit Reversal Training

Participants learn to identify when their tics occur and then learn a competing response to engage in instead of the 3 identified tics and then practice competing responses learned in session during the practice sessions throughout the week.