RecruitingNot ApplicableNCT06828939

Pulmonary Vein Isolation With the Single Shot Endoscopic Ultra-Compliant PFA Balloon for the Treatment of AF

Pulmonary Vein Isolation With the Single Shot Endoscopic Ultra-Compliant Pulsed Field Ablation Balloon for the Treatment of Atrial Fibrillation


Sponsor

CardioFocus

Enrollment

75 participants

Start Date

Dec 12, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is a prospective, single-arm First-in-Human study to demonstrate the safety and effectiveness of the CardioFocus OptiShot Pulsed Field Ablation System for catheter ablation of atrial fibrillation (AF). Patients with symptomatic paroxysmal (short-duration) AF who have not had a previous catheter ablation for AF will be considered for the study. Patients will be followed for one year after the initial ablation procedure.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria5

  • Recurrent symptomatic PAF with at least one documented episode
  • Failure or intolerance of at least one AAD
  • Age 18-75 years
  • Patient is indicated for an ablation procedure according to society guidelines or study site practice
  • Patient is willing and able to give informed consent/participate in baseline and follow-up assessments for the duration of the study

Exclusion Criteria1

  • overall good health as established by multiple criteria

Interventions

DEVICEpulsed field ablation

Pulsed field ablation using a ultra-compliant endoscopic PFA balloon.


Locations(1)

Na Homolce Hospital

Prague, Czech Republic, Czechia

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NCT06828939


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