STimulation to Activate RespIration

This trial is testing whether electrical stimulation of the diaphragm (the breathing muscle) can help people breathe better and potentially reduce the time they need mechanical ventilation. It targets patients who are in the ICU with acute respiratory failure — a sudden, severe inability to breathe on their own. The stimulation is delivered through a tube placed in the esophagus (food pipe). **You may be eligible if...** - You are 18 years or older - You are currently on mechanical ventilation or non-invasive breathing support in an ICU - Your breathing problems began within the past 2 weeks - Your blood oxygen levels are significantly low (meeting specific clinical criteria) **You may NOT be eligible if...** - Your breathing problem has been present for more than 2 weeks before needing respiratory support - You have conditions that would make the stimulation device unsafe to use Talk to your doctor to see if this trial is right for you.