Prone Positioning in ARDS: Predicting Neurological Complications Via Cerebral Hemodynamics

This study is investigating whether monitoring blood flow in the brain (cerebral hemodynamics) during prone positioning — where critically ill patients are placed face-down to improve lung function — can predict and help prevent neurological complications in people with severe ARDS (a life-threatening lung condition). **You may be eligible if...** - You are 18 or older - You meet the criteria for ARDS (acute respiratory distress syndrome) with a very low blood oxygen level (PaO2/FiO2 ratio below 150 mmHg) - You require prone ventilation as part of your ICU treatment - You are expected to need mechanical ventilation for more than 48 hours - A guardian or legally authorized representative has provided written consent **You may NOT be eligible if...** - You have injuries to your head, neck, or spine that prevent prone positioning - You have severe brain conditions such as hemorrhage, stroke, or brain tumors - Your condition is life-threatening enough to prevent participation Talk to your doctor to see if this trial is right for you.