Prone Positioning in ARDS: Predicting Neurological Complications Via Cerebral Hemodynamics
Changes in Cerebral Blood Flow Before and After Prone Position in Patients With ARDS Predict the Occurrence of Neurological Complications
Sichuan Provincial People's Hospital
50 participants
Mar 19, 2025
OBSERVATIONAL
Conditions
Summary
Prone Positioning in ARDS: Predicting Neurological Complications via Cerebral Hemodynamics
Eligibility
Inclusion Criteria4
- Age≥18 years
- Meet the diagnostic criteria for ARDS(Acute Respiratory Distress Syndrome),with PaO₂/FiO₂\<150 mmHg,and requiring prone ventilation
- Expected duration of mechanical ventilation\>48 hours
- Written informed consent obtained
Exclusion Criteria5
- Presence of contraindications to prone positioning(e.g.,head and neck injuries,spinal instability,severe intracranial hypertension)
- Severe neurological diseases(e.g.,cerebral hemorrhage,cerebral infarction,intracranial space-occupying lesions)that may affect the monitoring of cerebral hemodynamics
- Life-threatening ARDS
- Patients who are unable to undergo neurological assessment
- Poor image quality or absence of images
Interventions
Cerebral Blood Flow Monitoring Before and After Prone Ventilation in Patients with ARDS.Cerebral blood flow,intracranial pressure,and systemic hemodynamic monitoring were performed at the following time points:before prone positioning(T0),1 hour after prone ventilation(T1),12 hours after prone ventilation(T2),1 hour after returning to the supine position(T3),and 7 days after returning to the supine position(T4).
Locations(1)
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NCT06967285