RecruitingNCT06832631

VITUS Post-Market Registry

A Prospective PMCF Study of Paclitaxel Drug-coated Balloon Angioplasty for the Treatment of Symptomatic Peripheral Arterial Disease


Sponsor

OrbusNeich

Enrollment

284 participants

Start Date

May 22, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

To collect post marketing surveillance data on consecutive patients with peripheral arterial occlusive disease (PAOD) intended to be or treated by the VITUS peripheral drug-coated dilatation catheter when used according to the Instructions for Use and treating physician decision. Data will be collected in order to assess the long-term safety and performance of the VITUS peripheral drug-coated dilatation catheter in routine clinical practice.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Consecutive patients intended to be or treated by the VITUS peripheral drug-coated dilatation catheter as per physicians' decision and according to IFU in the setting of routine clinical care are entered into the registry
  • The lesion to be treated should be shorter than the nominal length of balloon at a reference vessel diameter of 2.0 mm up to 7.0 mm.
  • If lesion is longer than the individual balloon, more than one DCB can be used for longer lesions with the mandatory overlapping balloons of 10mm to avoid any geographical miss.
  • Rutherford clinical categories 2-5

Exclusion Criteria6

  • The patients are excluded from registration if ANY of the following conditions apply:
  • High probability of non-adherence to the follow-up requirements (due to social, psychological or medical reasons)
  • Currently participating in another investigational drug or device study in which a routine angiographic follow-up in peripheral arteries is planned
  • A life expectancy of <1year
  • Explicit refusal of participation in the registry
  • Residual stenosis >50% after vessel preparation

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Interventions

DEVICEPercutaneous Transluminal Angioplasty with a paclitaxel drug-coated balloon

Balloon angioplasty for the treatment of symptomatic peripheral arterial disease with a paclitaxel drug-coated balloon


Locations(13)

AZORG

Aalst, Belgium

AZ Sint-Blasius

Dendermonde, Belgium

ZOL Genk

Genk, Belgium

AZ Groennge

Kortrijk, Belgium

RZ Heilig Hart Tienen

Tienen, Belgium

AZ Jan Portaels

Vilvoorde, Belgium

Klinikum Lippe Detmold

Detmold, Germany

SRH Klinikum Karlsbad-Langensteinbach GmbH

Karlsbad, Germany

Singapore General Hospital

Singapore, Singapore

Hospital Universitario de Cabueñes

Gijón, Spain

Hospital General de Granollers

Granollers, Spain

Complejo Hospitalario Universitario de Ourense

Ourense, Spain

Hospital Universitario de Toledo

Toledo, Spain

View Full Details on ClinicalTrials.gov

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NCT06832631


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