RecruitingNot ApplicableNCT06838572

Effect of Remote Local Peripheral Nerve Cooling on Pain of Arterial Puncture


Sponsor

The Second Affiliated Hospital of Chongqing Medical University

Enrollment

100 participants

Start Date

Feb 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

In this project, volunteers will be recruited to cool the superficial skin of the axillary brachial plexus away from the puncture point, resulting in local peripheral nerve cooling, and observe its impact on the pain of arterial puncture.To explore the local peripheral nerve cooling treatment can produce controllable and reversible analgesic effect even if away from the wound, and provide a new nonpharmaceutical analgesic mode for clinical.


Eligibility

Inclusion Criteria6

  • 18 ~ 65 years old;
  • ASA I-II level;
  • Patients with perioperative invasive arterial blood pressure monitoring;
  • Right-handed;
  • Allen test was normal (palm color quickly turned red or returned to normal within 10 seconds after release of ulnar artery pressure);
  • Participate voluntarily and be able to understand and sign informed consent.

Exclusion Criteria7

  • Patients with a history of musculoskeletal, vascular, neurological or psychiatric disorders;
  • Patients with a history of diabetes or other systemic diseases
  • Patients who used any analgesic medication within the month before and during the study;
  • Patients with a history of smoking, alcohol or drug addiction;
  • Paraesthesia, scar, redness, damage, rash, etc. exist in the skin of the patient in the test area;
  • Patients whose surgical area overlaps with the cooling treatment or puncture area;
  • Female subjects are menstruating.

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Interventions

PROCEDURESkin cooling to 20°C

According to the group, copper parts at a constant temperature of 20°C were placed on the superficial skin of the brachial plexus for 15 minutes.

PROCEDURESkin cooling to 15°C

According to the group, copper parts at a constant temperature of 15°C were placed on the superficial skin of the brachial plexus for 15 minutes.

PROCEDURESkin cooling to 8°C

According to the group, copper parts at a constant temperature of 8°C were placed on the superficial skin of the brachial plexus for 15 minutes.

PROCEDURENo skin cooling

According to the group, copper parts at room temperature (23°C) were placed on the superficial skin of the brachial plexus for 15 minutes.


Locations(1)

The Second Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

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NCT06838572


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