CRYoablation for Small Tumors As Local Treatment - SIX Trial

This study is testing cryoablation — a procedure that freezes and destroys tumor tissue — as an alternative to surgery for small breast cancers. Instead of removing the tumor surgically, a needle is inserted to freeze the cancer in place. The study aims to see if this approach is as safe and effective as standard surgery. **You may be eligible if...** - You have been diagnosed with early-stage invasive breast cancer in a single location - Your tumor is 2 cm or smaller (T1 stage) - Your tumor is visible on ultrasound - You have a complete pathology report including hormone receptor and HER2 status - Surgery would have been recommended as your primary treatment **You may NOT be eligible if...** - You have cancer in multiple areas of the breast (multifocal or multicentric) - Your cancer involves the skin - Lymph nodes in your armpit are clearly affected - The tumor is less than 5 mm from the skin surface - You have already received chemotherapy or other cancer treatment before surgery - Your cancer has spread to other parts of the body Talk to your doctor to see if this trial is right for you.