RecruitingPhase 3NCT06840704

Immunonutrition Reduces Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer

Immunonutrition in Reducing Acute Esophagitis After Thoracic Radiotherapy in Lung Cancer: a Prospective, Randomized, Controlled, Open-label Clinical Trial


Sponsor

Hunan Cancer Hospital

Enrollment

121 participants

Start Date

Feb 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to evaluate the efficacy of immunonutrition in reducing acute esophagitis after thoracic radiotherapy in lung cancer.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a special nutrition formula (immunonutrition) taken before and during radiation therapy can reduce esophagitis — painful inflammation of the esophagus (food pipe) — which is a common and uncomfortable side effect of chest radiation for lung cancer. **You may be eligible if...** - You are 18 years old or older - You have been diagnosed with lung cancer (non-small cell or small cell) confirmed by a lab test - You are scheduled to receive radiation therapy to your chest, with the esophagus within the radiation zone - You can eat and drink normally by mouth - Your general health score (ECOG) is 0 or 1 **You may NOT be eligible if...** - You have certain serious organ problems - You cannot eat by mouth - You are pregnant or breastfeeding - You are receiving certain other treatments that would conflict with the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTOral immunonutrition

Oral immunonutrition (Oral Impact®, Nestlé), 250 ml per bottle, with a dosage of 2 bottles per day, starting on the day of radiotherapy and continuing for three weeks after radiotherapy.


Locations(6)

Hunan Cancer Hospital

Changsha, Hunan, China

Third Xiangya Hospital, Central South University

Changsha, Hunan, China

Xiangya Hospital of Central South University,

Changsha, Hunan, China

The First People's Hospital of Chenzhou

Chenzhou, Hunan, China

The Fisrt Affilated Hospital of University of South China

Hengyang, Hunan, China

Yueyang Central Hospital

Yueyang, Hunan, China

View Full Details on ClinicalTrials.gov

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NCT06840704


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