RecruitingPhase 2NCT06840899
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
Cannabinoid Modulation for Neurogenic Lower Urinary Tract Dysfunction in Spinal Cord Injury
Sponsor
University of Wisconsin, Madison
Enrollment
20 participants
Start Date
Feb 13, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
The goal of this feasibility study is to learn whether Cannabidiol (CBD) can improve urinary incontinence and other symptoms in people with recent spinal cord injury (SCI). Participants will take Epidiolex (purified CBD) for 90 days
Eligibility
Min Age: 18 Years
Inclusion Criteria5
- >18 years of age
- History of supra-sacral spinal cord injury of any mechanism
- Urinary incontinence with ≥2 episodes of urinary incontinence per day (outside of spinal shock)
- Willingness to participate in drug intervention trial
- English-speaking (able to provide consent and complete questionnaires)
Exclusion Criteria4
- History of intravesical Botox
- Actively taking >15 mg of Oxybutynin single dose or equivalent dose of alternative anticholinergic medication for bladder symptoms
- Use of Cannabis (any form) outside of study as determined by urine drug screen after washout period of 1 month if prior Cannabis use reported
- Thought or mood disorder aside from depression
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Interventions
DRUGCBD
Twice daily 100mg cannabidiol (CBD)
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06840899
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