H5N1 Milk Detection Study
Investigation of Impact of Milk Consumption on H5 Influenza Detection in Respiratory Specimens
Emory University
30 participants
May 9, 2025
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to determine whether drinking pasteurized milk (milk heated to kill harmful germs) that contains inactive particles of a flu virus called A(H5) could lead to the detection of the virus in the nose or throat. Inactive particles are not capable of causing disease. The results will help the Centers for Disease Control and Prevention (CDC) better understand how milk consumption could affect flu surveillance. Investigators also want to see if the body produces antibodies in response to this milk consumption.
Eligibility
Inclusion Criteria4
- Individuals aged 18-64 years
- BMI ≤ 35 kg/m2
- Able to understand and give informed consent (American English) and comply with study visits and procedures.
- In good general health based on medical history and the investigator's clinical judgment.
Exclusion Criteria9
- Symptoms of acute respiratory illness or conjunctivitis within 7 days
- Febrile illness in the previous 72 hours
- Recent influenza antiviral use (within 14 days)
- Immunosuppression due to illness or medications
- Current pregnancy or breastfeeding
- History of allergy or intolerance to milk or milk alternatives
- Consumption of raw (unpasteurized) milk within the previous 14 days
- Recent work (within 14 days) on a farm with animals known to be infected with A(H5) virus
- Previous receipt of A(H5) vaccine at any time
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
Milk to be used in the study will be obtained from the CDC. Pasteurized commercial milk likely to contain detectable A(H5N1) particles will be obtained from a source such as a recently affected dairy farm. The CDC Influenza Division laboratory (Viral, Surveillance, and Diagnosis Branch) will test the milk to confirm the presence of viral A(H5) RNA using a protocol developed and validated by the US FDA Agricultural Research Service. The US Food and Drug Administration (FDA) has indicated that the consumption of commercial pasteurized dairy products in the US is safe.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06850298