Influenza Clinical Trials

88 recruiting

Influenza Trials at a Glance

91 actively recruiting trials for influenza are listed on ClinicalTrialsFinder across 6 cities in 47 countries. The largest study group is Phase 1 with 18 trials, with the heaviest enrollment activity in Bethesda, Chicago, and Atlanta. Lead sponsors running influenza studies include National Institute of Allergy and Infectious Diseases (NIAID), Emory University, and Association Clinique Thérapeutique Infantile du val de Marne.

Browse influenza trials by phase

Treatments under study

About Influenza Clinical Trials

Looking for clinical trials for Influenza? There are currently 88 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Influenza trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Influenza clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 91 trials

Recruiting
Phase 3

Efficacy of Baloxavir Against Influenza in Hospitalized Patients: The INFLUENT Study (INpatients inFLUENza Treatment)

Influenza Disease; Flu
Dre Pauline Vetter484 enrolled1 locationNCT06653569
Recruiting
Not Applicable

Enhancing Maternal Vaccine Knowledge and Uptake: The InTroDuce-Programme Trial

KnowledgeVaccination UptakeInfluenza+1 more
Universiti Putra Malaysia351 enrolled4 locationsNCT06815250
Recruiting
Phase 3

A Surveillance Study of Susceptibility to Baloxavir Marboxil in Pediatric Participants With Influenza and Transmission of Influenza to Household Contacts

Influenza
Hoffmann-La Roche1,100 enrolled51 locationsNCT06094010
Recruiting
Phase 1

Quadrivalent Influenza HA Stem Vaccine VRC-FLUMOS0122-00-VP (SteMos1) With and Without ALFQ Adjuvant in Healthy Adults

Influenza PreventionPandemic Influenza Prevention
National Institute of Allergy and Infectious Diseases (NIAID)56 enrolled1 locationNCT07111078
Recruiting
Phase 4

Woodsmoke Exposure, Influenza Infection, and Nasal Immunity

InfluenzaSmoke Exposure
University of North Carolina, Chapel Hill112 enrolled1 locationNCT06841913
Recruiting

National Bacterial Meningitis Study in Children and Newborns

MeningitisChildren, OnlyNeonatal Infection+5 more
Association Clinique Thérapeutique Infantile du val de Marne10,000 enrolled1 locationNCT04664569
Recruiting

Screening for LID Clinical Studies Unit Healthy Volunteer Protocols

ZikaInfluenza
National Institute of Allergy and Infectious Diseases (NIAID)5,000 enrolled1 locationNCT01386424
Recruiting
Phase 1

First-in-Human Study of VNT-101: Safety, Tolerability, and Pharmacokinetics

Influenza
National Institute of Allergy and Infectious Diseases (NIAID)78 enrolled1 locationNCT07169318
Recruiting
Phase 2

High vs.Standard Dose Influenza Vaccine in Pediatric Solid Organ Transplant (SOT) Recipients

InfluenzaTransplantation InfectionImmunization; Infection
National Institute of Allergy and Infectious Diseases (NIAID)312 enrolled8 locationsNCT05947071
Recruiting
Not Applicable

GEneRating Mucosal Immunity After INfluenzA Infection and Vaccination in Lung and Lymphoid TissuE

Influenza
Imperial College London36 enrolled1 locationNCT06620185
Recruiting
Not Applicable

H5N1 Milk Detection Study

Influenza
Emory University30 enrolled1 locationNCT06850298
Recruiting
Phase 2

BPL-1357 Against H1N1 Influenza Virus Challenge

HumanInfluenza
National Institute of Allergy and Infectious Diseases (NIAID)129 enrolled2 locationsNCT07215858
Recruiting
Phase 2

A Phase 2 Trial Comparing Antiviral Treatments in Early Symptomatic Influenza

InfluenzaInfluenza, Human
University of Oxford3,000 enrolled4 locationsNCT05648448
Recruiting

Respiratory Virus Sampling and Repository

COVID-19Influenza
National Institute of Allergy and Infectious Diseases (NIAID)20,000 enrolled2 locationsNCT05266222
Recruiting

Natural History of Systemic and Nasal Mucosal Immunity to Influenza and SARS-CoV-2 in Adults After Vaccination

COVID-19Influenza
National Institute of Allergy and Infectious Diseases (NIAID)150 enrolled1 locationNCT04794829
Recruiting
Not Applicable

The INFLUENTIAL Trial- Evaluation of National Inpatient Influenza Vaccination Program

Influenza
University of Colorado, Denver22,000 enrolled2 locationsNCT05832307
Recruiting
Phase 1

pH1N1 Blinded Challenge Study

Influenza
National Institute of Allergy and Infectious Diseases (NIAID)90 enrolled2 locationsNCT07110532
Recruiting
Phase 3

A Study of mRNA-1018-H5 Pandemic Influenza Vaccine in Healthy Adults

Influenza
ModernaTX, Inc.4,000 enrolled36 locationsNCT07496450
Recruiting
Phase 1Phase 2

Safety and Immunogenicity of the Monovalent Influenza Vaccine A (H5N8) (Inactivated, Fragmented and Adjuvanted) in Adults and Older Adults

Avian Influenza A Virus
Butantan Institute700 enrolled5 locationsNCT06842173
Recruiting
Phase 1

Influenza Human Challenge Model

Influenza
Emory University80 enrolled2 locationsNCT05332899