RecruitingPhase 3NCT06850454

Olanzapine Versus Placebo for Moderately Emetogenic Chemotherapy

A Prospective Randomized, Double-blind Controlled Trial of Olanzapine Versus Placebo in Addition to Ondansetron Plus Dexamethasone As Antiemetic Prophylaxis in Patients Receiving Moderately Emetogenic Chemotherapy


Sponsor

Mahidol University

Enrollment

140 participants

Start Date

Jan 10, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A study comparing efficacy of olanzapine versus placebo to prevent nausea and vomiting from moderate emetic risk chemotherapy


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called olanzapine for people with chemotherapy induced nausea and vomiting. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGolanzapine

olanzapine 5 mg oral prior to chemotherapy on day 1 and daily on day 2-4

DRUGPlacebo

placebo 5 mg oral prior to chemotherapy on day 1 and daily on day 2-4


Locations(1)

Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok, Bangkok, Thailand

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NCT06850454


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