RecruitingNot ApplicableNCT06886451

Vomiting Prevention in Children With Cancer

Prevention of Vomiting in Pediatric Oncology Inpatients Using Machine Learning


Sponsor

The Hospital for Sick Children

Enrollment

1,332 participants

Start Date

Mar 18, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this single arm trial is to learn if a machine learning (ML) model predicting the risk of vomiting within the next 96 hours will impact vomiting outcomes in inpatient cancer pediatric patients. The main questions it aims to answer are whether an ML model predicting the risk of vomiting within the next 96 hours will: Primary 1\. Reduce the proportion with any vomiting within the 96-hour window Secondary 1. Reduce the number of vomiting episodes 2. Increase the proportion receiving care pathway-consistent care 3. Impact on number of administrations and costs of antiemetic medications Newly admitted participants will have a ML model predict the risk of vomiting within the next 96 hours according to their medical admission information. The prediction will be made at 8:30 AM following admission. Pharmacists will be charged with bringing information about patients' vomiting risk to the attention of the medical team and implementing interventions.


Eligibility

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying ML-based intervention for people with chemotherapy induced nausea and vomiting, pediatric cancer, and other related conditions. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERML-based intervention

For each patient, a ML model will predict the risk of vomiting within the next 96 hours. Patients will then receive care pathway-consistent interventions based on the ML model predictions.


Locations(1)

The Hospital for Sick Children

Toronto, Ontario, Canada

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NCT06886451


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