RecruitingNot ApplicableNCT06852508

TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use

TwySHE - An Mhealth Peer-navigator Intervention to Increase PrEP and Contraceptive Use Among Sexually Active Female University Students in Zambia: Study Protocol of a Hybrid Effectiveness-implementation Randomized Controlled Trial


Sponsor

University of Colorado, Denver

Enrollment

324 participants

Start Date

Feb 18, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to learn if the TwySHE intervention can increase the use of HIV prevention in at-risk female university students aged 18-24 in Zambia. The main question it aims to answer is: • Can a mhealth peer navigator intervention effectively promote HIV pre-exposure prophylaxis PrEP use among high-risk female students in Zambia? Researchers will compare the mhealth peer navigator intervention to treatment as usual to see if there are effects on female student's use and continuation of PrEP for HIV prevention. Participants in the intervention will be paired with a trained peer navigator who will offer education, social support, and help navigating the health systems to access PrEP and other sexual and reproductive health services. All participants in both arms will complete surveys at baseline, 6 months, and 12 months to evaluate health behaviors.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 24 Years

Inclusion Criteria5

  • Female
  • Aged 18 to 24 years
  • Current university student
  • Not diagnosed with HIV
  • Self-report of 3 more HIV risk factors

Exclusion Criteria6

  • Male
  • Less than 18 years of age
  • Greater than 24 years of age
  • Diagnosed with HIV
  • Less than 3 self-reported HIV risk behaviors
  • Not a university student

Interventions

BEHAVIORALTwySHE

Interpersonal support from trained peers to access and use PrEP and contraception.


Locations(1)

University of Zambia

Lusaka, Zambia

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NCT06852508


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