RecruitingPhase 1NCT06854042

A Study of Oral E1018 in Healthy Adult Participants

A First-In-Human, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose Study to Assess the Safety, Tolerability, and Pharmacokinetics of Oral E1018 in Healthy Adult Subjects

Sponsor

Eisai Inc.

Enrollment

32 participants

Start Date

Feb 26, 2025

Study Type

INTERVENTIONAL

Conditions

Healthy Participants Malaria

Summary

The primary purpose of the study is to evaluate the safety and tolerability of single ascending oral doses of E1018 in healthy adult participants and to evaluate the pharmacokinetics (PK) of E1018 in plasma and urine after single oral dose administration.

Eligibility

Min Age: 18 YearsMax Age: 55 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called E1018 and a drug called Placebo for people with healthy participants and malaria. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 55 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGE1018

Specified dose on specified days.

DRUGPlacebo

E1018 matching placebo on specified days.

Locations(1)

PPD Development, LP

Austin, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT06854042

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