RecruitingNot ApplicableNCT06857331

Perioperative Analgesia With Erector Spinae Plane Block in Liver Transplant Recipients

Optimization of Perioperative Analgesia With Erector Spinae Plane Block During Major Abdominal Surgeries in Patients With Impaired Liver Function

Sponsor

Bogomolets National Medical University

Enrollment

50 participants

Start Date

May 5, 2024

Study Type

INTERVENTIONAL

Conditions

Liver Transplant Erector Spina Plan Block

Summary

The goal of this clinical trial is to learn if ESP block is safe and effective for perioperative analgesia in patients undergoing liver transplant. The main question it aims to answer are Is ESP block safe and has a minimum side effects, like hematoma? Is it effective for perioperative analgesia? Researchers will compare the results to a group of patients who underwent liver transplants without any regional anaesthesia techniques. Participants will receive bilateral thoracic ESP block on the day of the transplantation with a subsequent bilateral catheterization.

Eligibility

Inclusion Criteria1

impaired liver function - cirrhosis or chronic liver disease with the development of hypocoagulation (APTT \> 35 sec, INR \> 1.5), thrombocytopenia, patients requiring major abdominal surgery, age \> 18 years, written consent to participate in the study was obtained

Exclusion Criteria1

Platelet count \<50x109, failed ESP catheterization unilateral or bilateral, failed epidural anesthesia attempt, history of allergy or hypersensitivity to local anesthetics, hepatopulmonary syndrome, patients on mechanical ventilation before surgery, patients on CRRT before surgery, refusal to participate in the study

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Interventions

PROCEDUREErector Spinae Plane Block using 0.2% ropivacaine

Bilateral thoracic ESP block on the day of the transplantation with a subsequent catheterization will be suggested for the patients. In case of their written consent for the participation in the study this procedure will be performed on the day of the operation. 0.2% ropivacaine is going to be used throughout all the perioperative period.