Liver Transplant Clinical Trials

126 recruitingLast updated: July 16, 2026

There are 126 actively recruiting liver transplant clinical trials across 38 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 1, Phase 3. Top locations include Lyon, France, Chicago, Illinois, United States, Philadelphia, Pennsylvania, United States. Updated daily from ClinicalTrials.gov.


Liver Transplant Trials at a Glance

126 actively recruiting trials for liver transplant are listed on ClinicalTrialsFinder across 6 cities in 38 countries. The largest study group is Not Applicable with 45 trials, with the heaviest enrollment activity in Lyon, Chicago, and Philadelphia. Lead sponsors running liver transplant studies include IRCCS Azienda Ospedaliero-Universitaria di Bologna, Assistance Publique - Hôpitaux de Paris, and RenJi Hospital.

Browse liver transplant trials by phase

Treatments under study

About Liver Transplant Clinical Trials

Looking for clinical trials for Liver Transplant? There are currently 30 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Liver Transplant trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Liver Transplant clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 126 trials

Recruiting
Not Applicable

Avoiding Recooling After Normothermic Machine Perfusion in Liver Transplantation

early allograft dysfunctionIschemia Reperfusion InjuryLiver Transplantation (LT)
The Mediterranean Institute for Transplantation and Advanced Specialized Therapies170 enrolled14 locationsNCT07692490
Recruiting

The Mycophenolate Pregnancy Registry

Heart Transplantation, Kidney Transplantation, Liver Transplantation, Autoimmune Diseases
Genentech, Inc.500 enrolled1 locationNCT01733082
Recruiting

Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection

Colorectal Cancer MetastaticLiver Transplant SurgeryColon Cancer Liver Metastases
Northwestern University80 enrolled1 locationNCT06698146
Recruiting
Not Applicable

Restrictive Fluid Management In Liver Transplantation (REFIL)

End-stage Liver Disease (ESLD)Liver Transplantation (LT)
Centre hospitalier de l'Université de Montréal (CHUM)866 enrolled4 locationsNCT07695363
Recruiting
Phase 2

Cytomegalovirus (CMV) Vaccine in Orthotopic Liver Transplant Candidates

Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)416 enrolled18 locationsNCT06075745
Recruiting

Effect of Preoperative CIMT on Hemodynamics During Liver Transplantation

Liver TransplantationCarotid Intima-Media Thickness
Dicle University54 enrolled1 locationNCT07660679
Recruiting
Not Applicable

ADDICTOlogical Intervention in LIVEr Transplantation Recipients

Liver TransplantationAlcohol Associated Liver Disease
University Hospital, Montpellier720 enrolled16 locationsNCT06472973
Recruiting
Phase 4

Influence of Human Albumin Supplementation on Kidney Dysfunction After Liver Transplantation

Acute Kidney InjuryLiver Transplantation
Rennes University Hospital400 enrolled8 locationsNCT06535945
Recruiting
Not Applicable

Rectus-Intercostal Fascial Plane Block for Liver Transplantation Donors

Postoperative PainLiver TransplantationLiving Donor
Istinye University64 enrolled1 locationNCT07233096
Recruiting
Phase 2

Early Signals of the Transition From Immune Quiescence to Activation in the Liver Allograft Microenvironment and in the Circulation

Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)100 enrolled10 locationsNCT07549503
Recruiting

Viability Assessment Using FMN Measured in Perfusate and Bile During Normothermic Machine Perfusion

Liver Transplant Disorder
The Cleveland Clinic850 enrolled1 locationNCT07315204
Recruiting
Not Applicable

Effect of Preoperative Oral Carbohydrate Loading on Postoperative Outcomes in Liver Transplant Patients

Liver TransplantLiver Transplant SurgeryLiver Transplantation+1 more
Medical University of Warsaw434 enrolled1 locationNCT07519057
Recruiting
Phase 2

Expanding Liver Transplant Immunosuppression Minimization Via Everolimus

Liver Transplant
National Institute of Allergy and Infectious Diseases (NIAID)340 enrolled8 locationsNCT06280950
Recruiting
Not Applicable

Evaluate the Performance of the Dexcom G7 Continuous Glucose Monitoring (CGM) System in Critically Ill Patients Undergoing Major Abdominal Surgery and Solid Organ Transplantation Which Require Blood Glucose Monitoring for Intensive Insulin Therapy.

Liver Transplant SurgerySolid-organ TransplantationDiabetes (Insulin-requiring, Type 1 or Type 2)+3 more
Institute for Clinical and Experimental Medicine62 enrolled1 locationNCT07611721
Recruiting

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

Chronic Kidney DiseaseLiver TransplantHepatitis C+1 more
Northwestern University1,000 enrolled1 locationNCT01644903
Recruiting

Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe

Liver CirrhosisLiver TransplantationAcute Liver Failure+1 more
University Medical Center Groningen10,000 enrolled2 locationsNCT07585890
Recruiting

A Survey on Growth Development in Children After Liver Transplantation

Growth, Development in Pediatric Liver Transplant Recipients
RenJi Hospital275 enrolled1 locationNCT07574398
Recruiting
Not Applicable

Effects of Terlipressin and Somatostatin on Portal Pressure in Patients Undergoing Living Donor Liver Transplantation

Liver TransplantationPortal Hypertension
Istanbul Medipol University Hospital50 enrolled1 locationNCT07304466
Recruiting
Not Applicable

Nutrition and Exercise Prehabilitation in Patients Awaiting Liver Transplantation

SarcopeniaLiver CirrhosisFrailty+3 more
Kalliopi Anna Poulia90 enrolled2 locationsNCT07561138
Recruiting
Not Applicable

Assessing Declined Liver Grafts With Normothermic Machine Perfusion to Reduce Transplant Waiting Time

SurgeryLiver DiseasesLiver Transplantation
Charite University, Berlin, Germany186 enrolled10 locationsNCT06874296