SPHERE Per-AF Post-Approval Study

This post-approval study is monitoring the real-world safety and effectiveness of the Sphere-9 catheter and Affera ablation system for treating persistent atrial fibrillation (AF) — a type of irregular heartbeat — using a procedure called pulmonary vein isolation. **You may be eligible if...** - You are 18 or older - You have recurrent symptomatic persistent AF (AF lasting more than 7 days but less than 12 months) - Your AF has not responded to, was not tolerated by, or you did not want at least one anti-arrhythmic drug - Your doctor is planning to perform a new (de novo) pulmonary vein isolation using the Sphere-9 catheter system **You may NOT be eligible if...** - You have long-standing persistent AF (lasting more than 12 months) - You have had a prior heart ablation procedure in the left atrium - You have a pacemaker, defibrillator, or similar cardiac implant - Your life expectancy is less than 36 months Talk to your doctor to see if this trial is right for you.