Observational Study About the Use of Perfusion Index to Use Vasopressor in Sepsis
Can Perfusion Index Indicate the Need of Vasopressor in ICU Patients with Sepsis and Septic Shock, Prospective Observational Study
Ain Shams University
40 participants
Aug 1, 2024
OBSERVATIONAL
Conditions
Summary
In this thesis we will use the current state of knowledge that PI can provide a reliable information about the state of peripheral microcirculation during the state of sepsis and septic shock in ICU patients and that can interfere with the timing of starting vasopressor treatment in sepsis and septic shock
Eligibility
Inclusion Criteria1
- \- All ICU patients with clinically suspected sepsis and septic shock ( signs include fever hypotension oliguria and confusion combined with culture results showing infection .Septic shock is a subset of sepsis involves persistent hypotension (mean arterial pressure ≥ 65 mm Hg, and a serum lactate level \> 18 mg/dL \[2 mmol/L)not responding to fluid resuscitation ) .
Exclusion Criteria6
- Pregnant females
- Patients on vasopressor or positive inotropic drugs
- Patients with hypothermia (defined as central temperature \<35°C).
- Patient with impairment of upper extremity circulation,(such as those who underwent radial artery harvesting for coronary artery bypass grafting or had suspected occlusion of the radial artery prior to surgery,)
- Patients had undergone an operation that involved the large arteries of the aortic arch.
- Patients with atherosclerosis .
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Interventions
vasopressor agents will be started in patients with sepsis who will not improved using the resuscitation fluids
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06860438