RecruitingNot ApplicableNCT06860880

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

Sponsor

UNC Lineberger Comprehensive Cancer Center

Enrollment

40 participants

Start Date

Jun 3, 2025

Study Type

INTERVENTIONAL

Conditions

Chronic Lymphocytic Leukemia Lymphoma Follicular Lymphoma Small Lymphocytic Lymphoma Marginal Zone Lymphoma Waldenstrom Macroglobulinemia Lymphoplasmacytic Lymphoma Cutaneous T Cell Lymphoma Indolent Lymphomas

Summary

This health services study will assess a multidisciplinary intervention program directed at fatigue mitigation among patients diagnosed with indolent lymphomas. Specifically, 30 subjects with chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and 10 subjects with Follicular Lymphoma (FL), marginal zone lymphoma (MZL), lymphoplasmacytic lymphoma (LPL), Waldenström's Macroglobulinemia, or Cutaneous T Cell Lymphoma (CTCL) will be included.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a personalized support program to help people with certain blood cancers who are experiencing cancer-related fatigue — extreme tiredness that does not go away with rest. **You may be eligible if...** - You are 18 or older - You have been diagnosed with indolent (slow-growing) lymphoma, Waldenström's Macroglobulinemia, or Cutaneous T-Cell Lymphoma - You are experiencing significant fatigue (as measured by a standard questionnaire) **You may NOT be eligible if...** - You have another active cancer - You have significant cognitive (memory or thinking) problems that would prevent you from understanding the study assessments Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERExercise

Each patient will receive an individualized exercise prescription that will encompass both aerobic and resistance training, with modifications as necessary to accommodate each patient's needs, abilities, and medical condition. For those not participating in any formal exercise at baseline, the exercise prescription will consist of a basic conditioning program targeting 150 minutes of moderate physical activity weekly with the assistance of a physical therapist if deemed appropriate.

OTHERDiet

Participants will undergo nutritional consultations with a registered dietitian who specializes in oncology. The dietitian will provide tailored dietary recommendations using evidence-based nutrition guidelines. Participants will also be screened ffor ormal nutrition based on American Society for Parenteral and Enteral Nutrition (ASPEN) guidelines as indicated.