Pulsed Electromagnetic Field Treatment With Dementia Patients

Exclusion Criteria15

• The patient lacks capacity to consent to study participation and no surrogate is available to provide consent
• The patient does not have a study partner who would be available for interview
• History of epileptic seizures or epilepsy
• Has Frontotemporal Dementia
• Currently taking medication that lowers the seizure threshold, excluding blood thinners
• Is currently taking anti-amyloid monoclonal antibodies (past treatment is allowed if termination of treatment occurred at least 3 months prior to the baseline visit).
• Presence of depression, bipolar disorder, a psychotic disorder, or any other neurological or psychiatric condition (whether now or in the past), which the Investigator finds as interfering with the study
• Severe agitation that would interfere with study procedures
• Alcoholism or substance use disorder as defined by Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) within last 5 years (addicted more than one year and or in remission less than 3 years) or severe sleep deprivation
• Major surgery (defined as any major abdominal, vascular or thoracic surgery requiring general anesthesia and resulting in a period of \>1 week hospitalization) within 4 weeks
• Head anatomy that interferes with the fit of the treatment device
• Participation in another clinical trial within the previous 30 days
• Metal implants in the head, (i.e., cochlear implants, implanted brain stimulators and neurostimulators, aneurysm clips) with the exception of metal implants in mouth
• Criteria to exclude participants from the blood draw study:
• Any condition that may significantly increase risks associated with blood draws