RecruitingEarly Phase 1NCT06864884

A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction

A Phase 1 Randomized, Placebo-Controlled, Blinded Study Evaluating the Safety, Tolerability, and Pharmacokinetics of ARC-001 in Participants Undergoing Third Molar Extraction


Sponsor

Arcato Laboratories, Inc.

Enrollment

30 participants

Start Date

Feb 26, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The study will test the investigational product gel against placebo (which contains no active ingredient) to determine if it is safe after wisdom tooth extraction. The main questions the study will answer are: 1. How much of the investigational product is absorbed in the blood? 2. Are there side effects?


Eligibility

Min Age: 18 YearsMax Age: 55 Years

Inclusion Criteria4

  • Able to provide informed consent
  • In generally good health
  • BMI 18 to 38kg/m²
  • Scheduled to undergo wisdom teeth extraction

Exclusion Criteria3

  • Serious medical condition
  • Clinically significant abnormal lab values
  • Blood donation in the last 60 days, or plasma donation in the last 7 days.

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Interventions

DRUGARC-001

Gel formulation containing investigational anesthetic.

DRUGPlacebo gel

Gel that contains no active ingredients.


Locations(1)

CenExel JBR

Salt Lake City, Utah, United States

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NCT06864884


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