Chlorhexidine Gluconate Versus Saline for Flushing the Surgical Area During Colorectal Cancer Surgery

This study is comparing two different liquids used to flush the surgical area during colorectal cancer surgery — a standard saltwater solution (saline) versus a disinfectant called chlorhexidine gluconate — to see which one better prevents infection. **You may be eligible if...** - You are between 18 and 85 years old - You have been diagnosed with colorectal cancer that can be removed by surgery (confirmed by CT or MRI scan) - You are in good general health (performance status 0 or 1) - Your overall health is suitable for surgery (ASA grade I–III) **You may NOT be eligible if...** - Your cancer has spread to other parts of the body (distant metastasis) - You have had previous abdominal surgery - You have been diagnosed with another cancer in the past 5 years and received radiation or chemotherapy - You have major liver or kidney problems, or you are pregnant - You have participated in another clinical trial in the past 6 months Talk to your doctor to see if this trial is right for you.