Dietary Modification In Inflammatory Bowel Disease Patients
Dietary Modification In Patients With Inflammatory Bowel Diseases And Its Impact In Gut Microbiome
University of Malaya
74 participants
Mar 1, 2025
INTERVENTIONAL
Conditions
Summary
This research project aimed to develop a culturally appropriate Asian Inflammatory Bowel Disease Diet for the Malaysian population, based on the Crohn's disease exclusion diet (CDED). The study will be conducted in inflammatory bowel disease patients in University Malaya Medical Centre, which are ulcerative colitis and Crohn's disease patients. The objectives of this study are to assess the impact of diet in clinical outcome and gut microbiota changes in patients with inflammatory bowel disease (IBD). The study duration spans 24 weeks, during which comprehensive follow-ups will be conducted at 0, 6, 12, and 24 weeks, respectively. At each follow-up session, participants will be requested to provide stool and blood samples for meticulous assessment of clinical and biochemical responses.
Eligibility
Inclusion Criteria3
- Confirmed diagnosis of Crohn's disease according to established clinical, endoscopic, and histological criteria.
- Mild to moderate diseases (150 to 220 points).
- Written informed consent obtained.
Exclusion Criteria3
- Presence of stoma.
- Surgery within 6 months prior to randomization.
- Patient on exclusive enteral nutrition (EEN).
Interventions
Participants will follow the quarter-quarter-half plate diet as per the Malaysian Healthy Plate guideline.
Participants will follow the Crohn's Disease Exclusion Diet (CDED), which consists of three phases with specific dietary restrictions.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06871267