RecruitingNot ApplicableNCT06871267

Dietary Modification In Inflammatory Bowel Disease Patients

Dietary Modification In Patients With Inflammatory Bowel Diseases And Its Impact In Gut Microbiome


Sponsor

University of Malaya

Enrollment

74 participants

Start Date

Mar 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This research project aimed to develop a culturally appropriate Asian Inflammatory Bowel Disease Diet for the Malaysian population, based on the Crohn's disease exclusion diet (CDED). The study will be conducted in inflammatory bowel disease patients in University Malaya Medical Centre, which are ulcerative colitis and Crohn's disease patients. The objectives of this study are to assess the impact of diet in clinical outcome and gut microbiota changes in patients with inflammatory bowel disease (IBD). The study duration spans 24 weeks, during which comprehensive follow-ups will be conducted at 0, 6, 12, and 24 weeks, respectively. At each follow-up session, participants will be requested to provide stool and blood samples for meticulous assessment of clinical and biochemical responses.


Eligibility

Min Age: 18 YearsMax Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether dietary changes can help reduce inflammation and improve symptoms in people with Crohn's disease — a condition that causes chronic inflammation of the digestive tract. **You may be eligible if...** - You have a confirmed diagnosis of Crohn's disease - Your disease activity is in the mild to moderate range (based on standard scoring) - You are willing to provide written consent **You may NOT be eligible if...** - You have a stoma (an opening in the abdomen for waste collection) - You had bowel surgery within the past 6 months - You are currently on exclusive enteral nutrition (being fed only through a liquid formula) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALGeneral Healthy Diet

Participants will follow the quarter-quarter-half plate diet as per the Malaysian Healthy Plate guideline.

BEHAVIORALCrohn's Disease Exclusion Diet (CDED)

Participants will follow the Crohn's Disease Exclusion Diet (CDED), which consists of three phases with specific dietary restrictions.


Locations(1)

Universiti Malaya Medical Centre

Kuala Lumpur, Petaling Jaya, Malaysia

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NCT06871267


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