A Study Evaluating the Safety and Tolerability of Artesunate in Patients With Pulmonary Arterial Hypertension

This study is evaluating the safety of artesunate — a drug originally used to treat malaria — in people with pulmonary arterial hypertension (PAH), a serious condition where blood pressure in the lungs is dangerously high, even when other standard medications have not provided enough relief. **You may be eligible if...** - You are between 18 and 75 years old - You have been diagnosed with pulmonary arterial hypertension (PAH) - You are already taking two or more approved PAH medications at their maximum tolerated doses and still have significant symptoms (WHO functional class II or III) **You may NOT be eligible if...** - You have serious other health conditions that the study doctor believes would make participation unsafe Talk to your doctor to see if this trial is right for you.