Open Pilot Trial of Adapted Cognitive Processing Therapy for Comorbid PTSD and Opioid Use Disorder

This study is testing a modified version of a well-known therapy called Cognitive Processing Therapy (CPT) for people who have both PTSD (post-traumatic stress disorder) and opioid use disorder — to see if trauma therapy can be delivered effectively within a harm reduction setting such as a syringe services program. **You may be eligible if...** - You are 18 years old or older - You regularly attend a syringe services program (at least 4 visits in the past month) - You meet criteria for opioid use disorder (OUD) and have been prescribed medication for it (such as methadone, buprenorphine, or naltrexone) in the past 30 days - You have experienced a traumatic event and have PTSD symptoms (score of 31+ on the PCL-5 checklist) - You can understand English **You may NOT be eligible if...** - You are at high risk for suicidal behavior - You have a current diagnosis of psychosis or bipolar disorder - You have cognitive difficulties that would interfere with participation - You are already receiving trauma-focused therapy (such as Prolonged Exposure or CPT) Talk to your doctor to see if this trial is right for you.