RecruitingPhase 1Phase 2NCT06873555

A Study of DC05F01 in Chinese Patients With Recurrent/Refractory Ovarian Cancer and Other Advanced Solid Tumors

Phase Ib/IIa Multicenter, Open-Label Study to Evaluate the Efficacy, Safety, and Pharmacokinetic Profile of DC05F01 in Patients With Recurrent/Refractory Ovarian Cancer and Other Advanced Solid Tumors


Sponsor

Heronova Pharmaceuticals

Enrollment

60 participants

Start Date

Sep 11, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This study is a multicenter, open-label, cohort expansion Phase Ib/IIa trial designed to evaluate the efficacy, safety, and pharmacokinetic (PK) profile of DC05F01 in patients with recurrent/refractory ovarian cancer and other advanced solid tumors.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new drug called DC05F01 in Chinese patients with advanced cancers — including ovarian cancer, small cell lung cancer, and other solid tumors — that have stopped responding to standard treatments. **You may be eligible if...** - You are 18 years old or older - You have advanced ovarian, fallopian tube, or primary peritoneal cancer that progressed during or within 6 months of platinum chemotherapy - OR you have limited-stage small cell lung cancer that did not progress after at least 4 cycles of platinum-based chemotherapy and radiation - OR you have another advanced solid tumor that has failed standard treatments - You are in good enough health to participate (ECOG performance status 0–1) - You have had previous debulking (tumor-removing) surgery for ovarian cancer **You may NOT be eligible if...** - You have an active serious infection, severe liver or kidney disease, or uncontrolled heart conditions - You are not willing to follow the study requirements or cannot sign consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGDC05F01

DC05F01 capsule


Locations(2)

The Fisrt Affiliated Hospital of Bengbu Medical University

Bengbu, Anhui, China

Hunan Cancer Hospital

Changsha, Hunan, China

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NCT06873555


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