Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study
Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study: Aim 2
Northwestern University
500 participants
Feb 1, 2025
INTERVENTIONAL
Conditions
Summary
Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria.
Eligibility
Inclusion Criteria10
- HIV Case Finding Intervention:
- Aged 15 to 24
- Male birth sex of any current gender identity
- Understand basic English, Yoruba, Hausa, Igbo or Pidgin English For the PrEP component, must also be HIV-negative
- HIV Treatment Intervention:
- Aged 15 to 24
- HIV seropositive
- Initiating ART for the first time at a Clinical Research Performance Site (CRPS) clinic or satellite clinic
- Understand basic English, Yoruba, Hausa, Igbo or Pidgin English
- Intention to remain a CRPS patient during follow-up
Exclusion Criteria2
- Unable to provide consent
- No parental permission if aged 15 and not emancipated
Interventions
Peer navigators will promote HIV testing in YMSM and linkage to care if HIV-positive
Motivational-interviewing to promote uptake of PrEP among those who test HIV-negative
Peer navigators will provide assistance and support to youth with HIV to optimize adherence to ART
Social media outreach to identify youth at risk for HIV
Text (SMS) messages to remind and encourage youth to adhere to their ART
Standard of care HIV treatment adherence
Locations(6)
View Full Details on ClinicalTrials.gov
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NCT06880224