RecruitingNot ApplicableNCT06880224

Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study

Intensive Combination Approach to Rollback the HIV Epidemic in Nigerian Youth (iCARE) Plus Effectiveness/Implementation Hybrid Study: Aim 2


Sponsor

Northwestern University

Enrollment

500 participants

Start Date

Feb 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Two combination interventions (HIV Case Finding Intervention and HIV Treatment Intervention), each with mHealth and Peer Navigation components, will be evaluated in two 48-week parallel hybrid effectiveness/implementation trials among youth aged 15-24 in Nigeria.


Eligibility

Min Age: 15 YearsMax Age: 24 Years

Plain Language Summary

Simplified for easier understanding

This study in Nigeria tests a combination program for young people aged 15–24 to address the HIV epidemic. It includes HIV testing and prevention (PrEP — a daily pill that prevents HIV infection) for HIV-negative young men, and HIV treatment support for those already living with HIV. **You may be eligible if (for HIV prevention/PrEP):** - You are a male (assigned male at birth) aged 15–24 - You are HIV-negative - You live in Nigeria and can communicate in English, Yoruba, Hausa, Igbo, or Pidgin English **You may be eligible if (for HIV treatment support):** - You are aged 15–24 - You are living with HIV - You are receiving or beginning HIV treatment **You may NOT be eligible if:** - You are outside the 15–24 age range - You do not meet the sex/gender or language requirements for the prevention component - You are already enrolled in another conflicting study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALTesting Peer navigation

Peer navigators will promote HIV testing in YMSM and linkage to care if HIV-positive

BEHAVIORALPrEP Intervention

Motivational-interviewing to promote uptake of PrEP among those who test HIV-negative

BEHAVIORALTreatment Peer Navigation

Peer navigators will provide assistance and support to youth with HIV to optimize adherence to ART

BEHAVIORALSocial Media Outreach

Social media outreach to identify youth at risk for HIV

BEHAVIORALSMS Test messaging

Text (SMS) messages to remind and encourage youth to adhere to their ART

OTHERAdherence standard of care

Standard of care HIV treatment adherence


Locations(6)

University of Uyo Teaching Hospital

Uyo, Akwa Ibom State, Nigeria

Federal Medical Center

Makurdi, Benue State, Nigeria

Taraba State Specialist Hospital

Jalingo, Taraba State, Nigeria

University of Nigeria Teaching Hospital

Enugu, Nigeria

Aminu Kano Teaching Hospital

Kano, Nigeria

Lagos University Teaching Hospital

Lagos, Nigeria

View Full Details on ClinicalTrials.gov

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NCT06880224


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