RecruitingNot ApplicableNCT06924073

Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV


Sponsor

University of Washington

Enrollment

1,920 participants

Start Date

Oct 16, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Ending the HIV epidemic for youth living with HIV will require implementation and optimization of evidence-based interventions that address barriers to treatment. The proposed implementation study will test a youth-led data-driven implementation strategy to scale-up an evidence-based Adolescent Transition Package (ATP) aimed at improving transition processes and post-transition clinical outcomes for youth living with HIV in Kenya. Clinics will be randomized to receive standard of care implementation through trainer of trainers or the youth-led data-driven implementation strategy alongside trainer of trainers. We will study whether the enhanced implementation strategy improves the number of youth who receive the ATP, the number of providers that initially chose to use the ATP, and the consistency with which the ATP is used over time. We will also evaluate the cost of the ATP and whether the ATP improves health outcomes among youth living with HIV, including viral suppression and retention in care. Healthcare workers at study sites will complete surveys, focus group discussions, interviews, and participate in continuous quality improvement processes. Youth will participate in surveys and focus groups, and have their routine medical records abstracted.


Eligibility

Min Age: 10 Years

Inclusion Criteria7

  • Healthcare providers
  • ≥18 years of age
  • Employed at one of the 32 facilities in the RCT
  • Provides HIV services to adolescents affiliated within their clinic Adolescents and youth living with HIV
  • Between 15-24 years of age (focus group discussions, surveys) or between 10-24 years of age (offered the intervention)
  • Receives HIV clinical care at one of the clinics included in the study
  • Attended clinic ≥1 time following intervention implementation

Exclusion Criteria2

  • Any individual who meets the following criteria will be excluded from participation in this study:
  • \- Conditions that would place the individual at increased risk or preclude the individual's full compliance with or completion of the study

Interventions

OTHERATP-Youth Enhanced Strategy (ATP-YES)

ATP-YES is a multi-component youth led implementation strategy that incorporates data audits and feedback, cyclical small tests of change and learning collaboratives


Locations(25)

Awendo Sub County Hospital

Awendo, Kenya

Uriri Sub County Hospital

Awendo, Kenya

Gatundu Level 5 Hospital

Gatundu, Kenya

Kiambu County Referral Hospital

Kiambu, Kenya

Wangige Sub-County Hospital

Kiambu, Kenya

Kikuyu (PCEA) Hospital

Kikuyu, Kenya

Nazareth Hospital

Limuru, Kenya

Arombe Dispensary

Migori, Kenya

Dede Health Centre

Migori, Kenya

Migori County Referral Hospital

Migori, Kenya

St Joseph Mission Hospital (Ombo)

Migori, Kenya

Baraka Dispensary (Nairobi)

Nairobi, Kenya

Embakasi Health Centre

Nairobi, Kenya

Kenyatta National Hospital/University of Nairobi

Nairobi, Kenya

Mama Lucy Kibaki Hospital

Nairobi, Kenya

Mbagathi District Hospital

Nairobi, Kenya

Mukuru Health Centre

Nairobi, Kenya

Pumwani Maternity Hospital

Nairobi, Kenya

Tabitha Medical Clinic

Nairobi, Kenya

Umoja Health Center

Nairobi, Kenya

Rongo Sub County Hospital

Rongo, Kenya

Verna Health Centre

Rongo, Kenya

Ruiru Sub-County Hospital

Ruiru, Kenya

Kiandutu Health Centre

Thika, Kenya

Thika Level 5 Hospital

Thika, Kenya

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NCT06924073


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