The Efficacy and Safety Study of CAR-T Cells for Functional Cure in HIV-1/AIDS Patients

This study tests whether a CAR-T cell therapy — a treatment where a patient's immune cells are genetically reprogrammed to target HIV — can achieve a "functional cure" for HIV. A functional cure means the virus is suppressed without the need for daily antiviral medication. **You may be eligible if:** - You are between 18 and 65 years old - You have confirmed HIV-1 infection - You have been on effective antiviral (antiretroviral) therapy for at least 2 years with undetectable virus (HIV-RNA less than 50 copies/mL) for the past 12 months - Your CD4 immune cell count is above 350 cells per microliter **You may NOT be eligible if:** - You have not been on sustained antiviral therapy or your virus is not suppressed - Your CD4 count is below the required threshold - You are pregnant - You have serious other health conditions that make CAR-T therapy unsafe - You are outside the 18–65 age range Talk to your doctor to see if this trial is right for you.