RecruitingNot ApplicableNCT06883578

Effect of Low Valine Diet on Body Weight and Metabolic Parameters

Sponsor

Shanghai Zhongshan Hospital

Enrollment

48 participants

Start Date

Feb 18, 2025

Study Type

INTERVENTIONAL

Conditions

Metabolic Associated Fatty Liver Disease Metabolic Diseases Overweight/Obesity

Summary

This study aimed to explore the effects of ordinary meal replacements and low-valine meal replacements on the weight and risk of related metabolic diseases in overweight/obese patients through a randomized double-blind controlled clinical trial.

Eligibility

Min Age: 16 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Long-term intermittent low valine meal replacement, Long-term intermittent normal meal replacement, and others for people with metabolic associated fatty liver disease, metabolic diseases, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 16 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIETARY_SUPPLEMENTShort-term continuous normal meal replacement

The normal meal replacement intake is calculated at 25kcal/kg body weight per person per day, with the calorie ratio for breakfast, lunch and dinner being 1:2:2. A meal replacement diet is given for 2 consecutive weeks.

DIETARY_SUPPLEMENTShort-term continuous low-valine meal replacements

The low valine meal replacement intake is calculated at 25kcal/kg body weight per person per day, with the calorie ratio for breakfast, lunch and dinner being 1:2:2. A meal replacement diet is given for 2 consecutive weeks.

DIETARY_SUPPLEMENTLong-term intermittent normal meal replacement

The normal meal replacement intake was calculated at 25 kcal/kg body weight per person per day, with the calorie distribution ratio of 1:2:2 for breakfast, lunch and dinner. A meal replacement diet was used for 2 consecutive days per week for 16 consecutive weeks.

DIETARY_SUPPLEMENTLong-term intermittent low valine meal replacement

The low valine meal replacement intake was calculated at 25 kcal/kg body weight per person per day, with the calorie distribution ratio of 1:2:2 for breakfast, lunch and dinner. A meal replacement diet was used for 2 consecutive days per week for 16 consecutive weeks.