RecruitingNot ApplicableNCT06884852

Ultrasound-guided Multilevel Erectorspinae Plane Block Versus Thoracic Epidural Analgesia for Prevention of Post Mastectomy Pain Syndrome for Breast Cancer Patients

Sponsor

National Cancer Institute, Egypt

Enrollment

44 participants

Start Date

Mar 20, 2025

Study Type

INTERVENTIONAL

Conditions

Breast Cancer Patients Ultrasound Multilevel Erector Spinae Plane Block Thoracic Epidural Analgesia Post Mastectomy Pain Syndrome

Summary

The aim of this study is to compare the analgesic efficacy of multilevel erector spinae plane block (ESPB) vs thoracic epidural in modified radical mastectomy (MRM) regarding duration of analgesia, postoperative opioid consumption, effect on intraoperative fentanyl consumption, postoperative numerical pain rating scale and quality of life for the next 6 months.

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two pain management techniques — a multilevel erector spinae nerve block (injecting local anesthetic along the back muscles) versus a thoracic epidural (injecting near the spine) — for preventing long-term chronic pain after mastectomy (breast removal surgery) in breast cancer patients. **You may be eligible if...** - You are a woman between 18 and 65 years old - You are scheduled for a modified radical mastectomy (complete breast removal with lymph node dissection) - Your BMI is between 20 and 35 kg/m² **You may NOT be eligible if...** - You refuse to participate - You have an allergy to local anesthetics or opioids used in the study - You have a history of chronic pain or psychological disorders - You have severe kidney disease, liver disease, or severe heart or lung disease - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGErector spinae plane block (ESPB)

Erector spinae plane block (ESPB) using multilevel injections of bupivacaine 0.25%. We will inject 15ml at the level of T2 and 15ml at the level of T5.

DRUGThoracic epidural block

Thoracic epidural block at level of T5 -T6 using 10 ml of bupivacaine 0.25% as a bolus followed by 5 ml bupivacaine 0.25% every 1-2 hours depending on the duration of surgery and the response of the patient.