Pain Syndrome Clinical Trials

161 recruitingLast updated: June 17, 2026

There are 161 actively recruiting pain syndrome clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Istanbul, Turkey (Türkiye), Boston, Massachusetts, United States, Cairo, Egypt. Updated daily from ClinicalTrials.gov.


Pain Syndrome Trials at a Glance

161 actively recruiting trials for pain syndrome are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 95 trials, with the heaviest enrollment activity in Istanbul, Boston, and Cairo. Lead sponsors running pain syndrome studies include Cairo University, Istanbul University, and Riphah International University.

Browse pain syndrome trials by phase

Treatments under study

About Pain Syndrome Clinical Trials

Looking for clinical trials for Pain Syndrome? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pain Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pain Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 161 trials

Recruiting

Intracept Minimally-invasive PROcedure for VErtebrogenic Back Pain

Chronic Low-back PainVertebrogenic Pain Syndrome
Boston Scientific Corporation1,500 enrolled18 locationsNCT06827262
Recruiting

MRI Study of Musculoskeletal Function

Patellofemoral Pain SyndromeAbnormalitiesImaging
National Institutes of Health Clinical Center (CC)750 enrolled1 locationNCT00051857
Recruiting

Genetic Study of Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Interstitial CystitisPainful Bladder Syndrome (PBS)Chronic Prostatitis (CP)+2 more
Boston Children's Hospital500 enrolled1 locationNCT00499317
Recruiting
Phase 3

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

Complex Regional Pain Syndrome Type I
Ambros Therapeutics, Inc.270 enrolled12 locationsNCT07210515
Recruiting

The Effect of Unstable Loads on Scapular Kinematics and Muscle Activation During Overhead Press in Overhead Athletes With Subacromial Pain Syndrome

Subacromial Pain Syndrome
National Yang Ming Chiao Tung University27 enrolled1 locationNCT07646899
Recruiting
Not Applicable

Supraspinal Processing of Sensory Aspects of Pain

Musculoskeletal PainFibromyalgiaFunctional Abdominal Pain Syndrome+2 more
Children's Hospital Medical Center, Cincinnati255 enrolled1 locationNCT05814497
Recruiting
Phase 4

Dex & Mastectomy Pain

Post-Mastectomy Chronic Pain Syndrome
McGill University Health Centre/Research Institute of the McGill University Health Centre170 enrolled1 locationNCT07556952
Recruiting
Not Applicable

Oxiblume:CoQ10 (Ralivia) Therapy for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Chronic Pelvic Pain Syndrome (CPPS)
G.Gennimatas General Hospital100 enrolled1 locationNCT07629505
Recruiting
Phase 1

Simulation-Free Celiac Plexus Pain Ablation Using Stereotactic Body Radiotherapy (SBRT) in Participants With Cancer-Related Celiac Pain

Pancreatic CancerRetroperitoneal Pain Syndrome
Case Comprehensive Cancer Center5 enrolled1 locationNCT07117032
Recruiting
Not Applicable

Popliteus Muscle Release Versus Kinesio Taping

Patellofemoral Pain Syndrome
Cairo University48 enrolled1 locationNCT07290296
Recruiting
Not Applicable

Isokinetic Training With Blood Flow Restriction for Patellofemoral Pain Syndrome

Patellofemoral Pain Syndrome
Nanjing Mingzhou Rehabilitation Hospital60 enrolled1 locationNCT07600827
Recruiting
Not Applicable

Enhancing Exercise Adherence Among Patients With Lateral Hip Pain

Hip painGreater Trochanter Pain Syndrome
Loughborough University60 enrolled1 locationNCT07597343
Recruiting
Phase 1

STTEPP: Safety, Tolerability and Dose Limiting Toxicity of Lacosamide in Patients With Painful Chronic Pancreatitis

Pancreatic SurgeryChronic PainChronic Pancreatitis+7 more
Indiana University24 enrolled5 locationsNCT05603702
Recruiting
Not Applicable

Investigation of PEMF Therapy for Female Patients With IC/BPS

Interstitial CystitisBladder Pain SyndromeChronic Interstitial Cystitis
Wake Forest University Health Sciences75 enrolled1 locationNCT05149573
Recruiting
Not Applicable

Evaluation of TENEX for Greater Trochanteric Pain Syndrome (GTPS)

greater trochanteric pain syndrome
Montefiore Medical Center150 enrolled1 locationNCT05710627
Recruiting
Not Applicable

Effect of Occlusal Splint on Head and Neck Muscles in Patients With Bruxism and Myofascial Pain

masticatory muscle pain,BruxismMyofacial Pain Syndrome+1 more
Istanbul University40 enrolled1 locationNCT07090551
Recruiting
Not Applicable

COMPARISON OF THREE TREATMENT MODALITIES IN MYOFASCIAL PAIN SYNDROME

myofascial pain syndrome
ALİEMAN60 enrolled1 locationNCT07511751
Recruiting
Not Applicable

Prednisone for CRPS in Distal Radius Fracture

Distal Radius FracturesComplex Regional Pain Syndromes
University of British Columbia40 enrolled1 locationNCT06453447
Recruiting
Not Applicable

New Approaches to Nerve Stimulation Therapy for Bladder Pain Syndrome

Bladder Pain Syndrome
Walter Reed National Military Medical Center5 enrolled1 locationNCT06204874
Recruiting

Interoceptive Awareness and Function in Adolescents With Chronic Pain

Pain, ChronicChronic PainChronic Pain Syndrome
Connecticut Children's Medical Center49 enrolled1 locationNCT07325110