Pediatric Cancer Clinical Trials

70 recruitingLast updated: June 17, 2026

There are 70 actively recruiting pediatric cancer clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4. Top locations include Memphis, Tennessee, United States, Philadelphia, Pennsylvania, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Pediatric Cancer Trials at a Glance

70 actively recruiting trials for pediatric cancer are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 35 trials, with the heaviest enrollment activity in Memphis, Philadelphia, and Boston. Lead sponsors running pediatric cancer studies include Children's Hospital of Philadelphia, St. Jude Children's Research Hospital, and UNC Lineberger Comprehensive Cancer Center.

Browse pediatric cancer trials by phase

Treatments under study

About Pediatric Cancer Clinical Trials

Looking for clinical trials for Pediatric Cancer? There are currently 69 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pediatric Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pediatric Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 70 trials

Recruiting

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

Pediatric Cancer
National Cancer Institute (NCI)5,000 enrolled1 locationNCT00001186
Recruiting

Response to Influenza Vaccination in Pediatric Oncology Patients

Hematologic MalignancyPediatric CancerTransplant-Related Cancer
St. Jude Children's Research Hospital150 enrolled1 locationNCT05384288
Recruiting

CAYA Cancer Prospective Cohort Study

CancerPediatric CancerAcute Lymphoblastic Leukemia ALL+1 more
Resonance, Inc.6,000 enrolled3 locationsNCT07632014
Recruiting
Not Applicable

Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

Pediatric Cancer
Nemours Children's Clinic350 enrolled3 locationsNCT05294302
Recruiting

Post Mortem Tissue Donation of Pediatric Tumor Tissues and Cells

Pediatric Cancer
Ann & Robert H Lurie Children's Hospital of Chicago150 enrolled1 locationNCT05120518
Recruiting

LIFE Cancer Survivorship Database for Pediatric Cancer

Pediatric Cancer
Children's Hospital Los Angeles5,000 enrolled1 locationNCT01518400
Recruiting
Not Applicable

Multisite Implementation of COMPRENDO

Pediatric Cancer
University of California, San Diego450 enrolled4 locationsNCT06055296
Recruiting
Not Applicable

Virtual Reality for Children in Radiotherapy (REVER)

Proton TherapyVirtual RealityPediatric Cancer
Centre Antoine Lacassagne47 enrolled1 locationNCT04934293
Recruiting
Phase 1Phase 2

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

Hepatocellular CarcinomaRefractory Solid TumorPediatric Solid Tumor+3 more
St. Jude Children's Research Hospital64 enrolled2 locationsNCT05468359
Recruiting
Phase 2Phase 3

Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.

All Types of Pediatric Cancer
Universität Duisburg-Essen56 enrolled1 locationNCT04765020
Recruiting
Not Applicable

Video Inspired Discussions About Ethical Outcomes in Pediatrics

Pediatric Cancer
Massachusetts General Hospital567 enrolled4 locationsNCT06786104
Recruiting

UNC Childhood, Adolescent, and Young Adult Cancer Cohort

CancerSurvivorshipCancer, Metastatic+1 more
UNC Lineberger Comprehensive Cancer Center500 enrolled1 locationNCT05096923
Recruiting
Not Applicable

Development and Evaluation of a Screening Approach for Sexual Dysfunction in AYA Patients With and Surviving Childhood Cancer

SurvivorshipPediatric Cancer
University of Colorado, Denver205 enrolled2 locationsNCT05524610
Recruiting
Not Applicable

Questionnaire on Congenital Cancer Signs Through Self-Assessment

Pediatric CancerHereditary Cancer SyndromesCancer Predisposition Syndromes+1 more
Insel Gruppe AG, University Hospital Bern205 enrolled1 locationNCT07378423
Recruiting
Not Applicable

Effect of Guided Imagery on Chemotherapy-related Nausea and Vomiting

Pediatric CancerChemotherapy Induced Nausea and Vomiting
Baskent University40 enrolled1 locationNCT06120764
Recruiting
Not Applicable

Feasibility and Acceptability of Internet-based Parent-child Interaction Therapy (I-PCIT) in Pediatric Cancer

OncologyPediatric CancerDisruptive Behavior
Johns Hopkins All Children's Hospital300 enrolled1 locationNCT06346782
Recruiting

Coping and Attachment in Pediatric Oncohematology

Pediatric CancerCoping BehaviorRelationship, Parent Child
Fondazione IRCCS Policlinico San Matteo di Pavia60 enrolled3 locationsNCT06858163
Recruiting
Not Applicable

The EFFECT of VİRTUAL REALİTY HEADSETS on ANXİETY, FEAR and PHYSİOLOGICAL PARAMETERS in CHİLDREN With CANCER UNDERGOİNG INTRATHECAL CHEMOTHERAPY

Pediatric Cancer
TC Erciyes University20 enrolled1 locationNCT07537062
Recruiting
Not Applicable

Massage Impact on Sleep in Pediatric Oncology

CancerAcute Myeloid LeukemiaChemotherapy Effect+3 more
Children's Hospital of Philadelphia70 enrolled2 locationsNCT06892158
Recruiting
Phase 2

Selpercatinib Pre-RAI in Patients With RET Fusion Thyroid Cancer (RAISE)

CancerPediatric CancerDifferentiated Thyroid Cancer+1 more
Children's Hospital of Philadelphia13 enrolled4 locationsNCT06458036