Texture and Color Enhancement Imaging (TXI) for Inflammation Assessment in Patients With Inflammatory Bowel Diseases
Texture and Color Enhancement Imaging (TXI) for Real-time Prediction of Histologic Changes in Patients With Inflammatory Bowel Diseases: a Comparison of White Light Endoscopy (WLE) Versus TXI
University of Ulm
80 participants
May 8, 2024
INTERVENTIONAL
Conditions
Summary
In the context of the COLORIZE study, it is being tested whether the endoscopic light mode Texture and Color Enhancement Imaging (TXI) is non-inferior to the standard White Light Endoscopy (WLE) in assessing inflammatory activity in patients with Inflammatory Bowel Disease (IBD). For this purpose, ileocolonoscopy is performed on patients diagnosed with IBD, and standardized image documentation will be carried out in both WLE and TXI modes. Step biopsies are taken, and clinically validated, endoscopic, and histological scores are used.
Eligibility
Inclusion Criteria2
- Histologically confirmed inflammatory bowel disease (ulcerative colitis or Crohn\'s disease)
- Age ≥ 18 years
Exclusion Criteria6
- Post (procto-) colectomy
- Endoscopically impassable stenosis in the left hemi-colon
- ASA status \> 2 points
- BBPS \< 6 points (or \< 2 points per segment)
- Severe coagulation disorder
- Pregnancy, lactation
Interventions
Experimental use of TXI mode compared to standard use of WLE to assess inflammatory activity in patients with IBD during ileocolonoscopy. Both endoscopy modes are used during the same ileocolonoscopy on the same patient.
Locations(1)
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NCT06892990