Colitis Ulcerative Clinical Trials

24 recruiting

Frequently Asked Questions

Common questions about Colitis Ulcerative clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 24 trials

Recruiting

A Real-World Study of Guselkumab in Chinese Participants With Ulcerative Colitis

Colitis Ulcerative
Xian-Janssen Pharmaceutical Ltd.200 enrolled1 locationNCT07302360
Recruiting
Phase 3

A Long-term Extension (LTE) Study of Guselkumab in Pediatric Participants

Colitis UlcerativeArthritis, PsoriaticCrohns Disease+1 more
Janssen Research & Development, LLC196 enrolled30 locationsNCT06663332
Recruiting

A Study to Observe Real-world Evidence of Guselkumab Treatment in Participants With Ulcerative Colitis and Crohn's Disease in the United Kingdom (UK)

Crohn's DiseaseInflammatory Bowel DiseaseColitis Ulcerative
Janssen-Cilag Ltd.220 enrolled1 locationNCT07242248
Recruiting

A Study to Generate Real-world Evidence of Guselkumab Effectiveness in Inflammatory Bowel Disease in Germany

Crohn's DiseaseInflammatory Bowel DiseaseColitis Ulcerative
Janssen-Cilag G.m.b.H400 enrolled1 locationNCT07102368
Recruiting

A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis

Crohn DiseaseColitis Ulcerative
Janssen Scientific Affairs, LLC1,056 enrolled1 locationNCT04372108
Recruiting
Phase 2Phase 3

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

Colitis Ulcerative
Bristol-Myers Squibb120 enrolled90 locationsNCT05076175
Recruiting
Phase 2

A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis

ColitisInflammatory Bowel DiseasesUlcerative Colitis+1 more
Spyre Therapeutics, Inc.645 enrolled126 locationsNCT07012395
Recruiting
Phase 2

A Study to Investigate Efficacy and Safety of SAR441566 in Patients With Ulcerative Colitis

Colitis Ulcerative
Sanofi204 enrolled110 locationsNCT06867094
Recruiting
Phase 3

A Protocol of Icotrokinra Therapy in Adult and Adolescent Participants With Moderately to Severely Active Ulcerative Colitis

Colitis Ulcerative
Janssen Research & Development, LLC882 enrolled301 locationsNCT07196748
Recruiting
Not Applicable

Acceptability, Adherence, and Impact on the Bioavailability of Iron and Zinc of the Dietary Supplements Goodphyte IB Defense and Goodphyte Immunity in Adults With Chronic Diseases.

Multiple SclerosisAnemiaIBD+2 more
University of Thessaly100 enrolled1 locationNCT07380022
Recruiting

Magnesium in Gastrointestinal Disease

Ileostomy - StomaBile Acid MalabsorptionColitis Ulcerative+9 more
University of Aarhus120 enrolled1 locationNCT07338565
Recruiting

Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis

Sleep QualityGastrointestinal MicrobiomeColitis Ulcerative+1 more
Xijing Hospital152 enrolled1 locationNCT06359808
Recruiting
Phase 3

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

Crohn DiseaseColitis Ulcerative
Merck Sharp & Dohme LLC1,380 enrolled37 locationsNCT06651281
Recruiting

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

Colitis Ulcerative
Pfizer300 enrolled22 locationsNCT06398626
Recruiting
Phase 1

A First-time in Human (FTIH) Study to Evaluate Safety, Tolerability, Pharmacokinetics and Target Engagement of GSK4528287 in Healthy Participants

Colitis Ulcerative
GlaxoSmithKline48 enrolled1 locationNCT06681181
Recruiting
Not Applicable

Diet Intervention Treatment for Active Ulcerative Colitis

Colitis Ulcerative
Mount Sinai Hospital, Canada20 enrolled1 locationNCT04121806
Recruiting

Therapeutic Endpoint in Pediatric IBD Conditions

Inflammatory Bowel DiseasesCrohn DiseaseColitis Ulcerative
Children's National Research Institute60 enrolled1 locationNCT06065228
Recruiting
Phase 3

Comparison of Medical RESCUE Strategies for Patients With Steroid-refractory Acute Severe Ulcerative Colitis

Colitis Ulcerative
McMaster University134 enrolled1 locationNCT06660693
Recruiting

A Study to Learn About the Effectiveness of Etrasimod in People With Ulcerative Colitis

Colitis Ulcerative
Pfizer360 enrolled31 locationsNCT06294925
Recruiting

Investigation of the Correlation Between Polyamine Levels and Their Key Enzymatic Activities in Association With Inflammatory Bowel Disease Progression

Inflammatory Bowel DiseasesCrohn DiseaseColitis Ulcerative+2 more
Xijing Hospital146 enrolled1 locationNCT06995170