RecruitingNCT06894095

Dongzong Cardiovascular Bio-imaging Registry Study


Sponsor

Jinling Hospital, China

Enrollment

50,000 participants

Start Date

May 24, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The DAILY project is a large-scale, multicenter, prospective initiative designed to establish a comprehensive bio-imaging database that integrates multidimensional data, including living environments, psychosocial and cognitive assessments, advanced lung and cardiovascular imaging, multi-omics profiles, clinical medication and surgical records, and health outcomes. Leveraging this extensive, multiscale dataset, the project aims to elucidate the intricate interplay between genetic biology and environmental factors in driving downstream biological alterations, thereby shaping lung and cardiovascular structural and functional phenotypes, and ultimately influencing the onset and progression of cardiovascular diseases (CVD). Through a systematic exploration and understanding of this complex network, the project seeks to identify critical intervention points and develop innovative strategies for the prevention and management of CVD.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Aged ≥18 years
  • Coronary CT angiography performed
  • Informed consent acquired

Exclusion Criteria5

  • Unable to complete the follow-up
  • Serious chronic kidney disease (eGFR< 30 ml/min/1.73 m2)
  • Serious liver disease or dysfunction (chronic active hepatitis and cirrhosis, or aspartate aminotransferase (AST) or alanine transaminase (ALT) > 3 times the upper limit of normal)
  • Not appropriate to be tested due to birth planning, allergies, acute thyroid storm, etc.
  • Suspected or known infectious diseases, such as hepatitis B virus (HBV), human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS), and Treponema pallidum (syphilis), etc.

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Locations(1)

Longjiang Zhang

Nanjing, Jiangsu, China

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NCT06894095


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