Electroencephalogram Predicts Post-operative Delirium
Frontal-temporal EEG During Anesthesia Recovery Predicts Postoperative Delirium in Neurosurgery: a Single-center, Prospective, Observational Study
Beijing Sanbo Brain Hospital
137 participants
Mar 1, 2025
OBSERVATIONAL
Conditions
Summary
The goal of this observational study is to investigate the predictive value of sub-hairline electroencephalography (EEG) during anesthesia recovery for postoperative delirium (POD). The main question to be answered is: * Can sub-hairline EEG measured during anesthesia recovery serve as a reliable predictor of POD? Adult patients undergoing elective craniotomy and admitted to the ICU will be enrolled. Sub-hairline EEG will be monitored until ICU discharge.
Eligibility
Inclusion Criteria4
- Age ≥ 18 years
- Planned elective neurosurgical surgery
- ASA physical status I-II
- Signed informed consent
Exclusion Criteria7
- Known neurological or psychiatric disorders (e.g., epilepsy, Parkinson's disease)
- Preoperative cognitive impairment (MMSE score \< 24)
- Long-term use of central nervous system drugs (e.g., antidepressants, antipsychotics)
- Language barriers
- History of craniotomy within the last 12 months
- Inability to place frontal-temporal electrodes due to conditions such as frontal skin injury, severe agitation, or a coronal incision for surgery
- Pregnant or breastfeeding women
Interventions
Participants will receive standard postoperative care as per institutional protocols, including neuromonitoring, delirium screening, and ICU management. The study will not alter or assign any treatments but will analyze the association between sub-hairline EEG parameters and postoperative delirium (POD) outcomes
Locations(2)
View Full Details on ClinicalTrials.gov
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NCT06894238