RecruitingNot ApplicableNCT06900452

The Effect of Pistachio-Rich Breakfast Meals on Cognitive Function in Healthy Older Adults

A Randomized Controlled Trial to Investigate the Cognitive, Vascular, Neural and Biochemical Effects of Acute Pistachio Intervention in Older Adults


Sponsor

University of Reading

Enrollment

52 participants

Start Date

Mar 6, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study aims to investigate the effect of a breakfast meal containing varying serving sizes (doses) of pistachio nuts on cognitive function throughout the course of the day in healthy ageing adults aged 65-80.


Eligibility

Min Age: 65 YearsMax Age: 80 Years

Inclusion Criteria6

  • - 80 years old
  • Fruit \& veg intake less than or equal to 4 servings per day
  • Not regularly consuming more than 3 servings of fish per week
  • Adequate English language and visual \& auditory acuity to perform the cognitive tasks
  • Normal BMI for age
  • Normal MMSE performance between 26-30

Exclusion Criteria8

  • Being diagnosed with psychological or psychiatric disorders
  • ADHD or dyslexia
  • Any food allergy or intolerance
  • Use of medications and dietary supplements that may impact study results
  • Antibiotic use within the last 3 months
  • Adherence to vegan or vegetarian diets, or other specific diets that may impact study outcomes
  • Being diagnosed with cardiometabolic disease (including type II diabetes and cardiovascular disease), or suffer from untreated hypertension or thrombosis related disorders
  • Taking blood thinners

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Interventions

DIETARY_SUPPLEMENT0.5 serving of pistachios

The equivalent of 0.5 servings (15g) of shelled, roasted pistachio nuts, crushed and mixed into a muesli-based breakfast meal for consumption. Ingredients: 15g pistachio, 35g muesli base, 150g full fat natural yoghurt, 15g unsalted butter (melted), 10g unflavoured whey powder

DIETARY_SUPPLEMENT1 serving of pistachios

The equivalent of 1 serving (30g) of shelled, roasted pistachio nuts, crushed and mixed into a muesli-based breakfast meal for consumption. Ingredients: 30g pistachio, 35g muesli base, 150g full fat natural yoghurt, 10g unsalted butter (melted), 5g unflavoured whey powder

DIETARY_SUPPLEMENT2 servings of pistachios

The equivalent of 2 servings (60g) of shelled, roasted pistachio nuts, crushed and mixed into a muesli-based breakfast meal for consumption. Ingredients: 60g pistachios, 25g muesli base, 150g low fat natural yoghurt

DIETARY_SUPPLEMENTPlacebo

Macronutrient-matched placebo breakfast meal. Ingredients: 40g muesli base, 150g full fat natural yoghurt, 25g unsalted butter (melted), 15g unflavoured whey powder


Locations(1)

Nutrition, Cognition & Health Lab, School of Psychology and Clinical Language Sciences, University of Reading

Reading, Berkshire, United Kingdom

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NCT06900452


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