RecruitingPhase 3NCT06902714

Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty

Evaluating the Effects of Oral Tranexamic Acid on Short Term Postoperative Outcomes Following Total Shoulder Arthroplasty: A Randomized Control Trial


Sponsor

University of Alabama at Birmingham

Enrollment

60 participants

Start Date

Apr 20, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this clinical trial is to evaluate the short-term clinical outcomes of patients undergoing total shoulder arthroplasty who receive an extended postoperative course of oral tranexamic acid


Eligibility

Min Age: 18 YearsMax Age: 79 Years

Inclusion Criteria1

  • Skeletally mature patients (ages 18-79) undergoing primary total shoulder arthroplasty

Exclusion Criteria1

  • Patients with Cancer, venous thromboembolism, stroke, heart disease, pregnant or nursing, allergic to TXA, current tobacco use, anticoagulants other than aspirin.

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Interventions

DRUGoral tranexamic acid

one group of subjects will receive oral tranexamic acid and the other will receive oral placebo

DRUGPlacebo

one group of randomized subjects will receive placebo and the other will receive oral tranexamic acid


Locations(1)

University of Alabama at Birmingham

Birmingham, Alabama, United States

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NCT06902714


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