RecruitingPhase 4NCT06903546

The Effect of Propolis Administration on Cholesterol Level in Diabetic Type 2 Patients

The Effect of Propolis Administration on Low Density Lipoprotein and High Density Lipoprotein in Diabetic Type 2 Patients in Central Jakarta

Sponsor

Indonesia University

Enrollment

64 participants

Start Date

Mar 18, 2025

Study Type

INTERVENTIONAL

Conditions

Diabetes Mellitus, Type 2

Summary

The goal of this clinical trial is to learn if propolis administration works to change the level of Low Density Lipoprotein (LDL) and High Density Lipoprotein cholesterol (HDL) in diabetic type 2 patients. The main questions it aims to answer are: \- Is giving 1 drops/ 10kg/ times, twice daily for 8 weeks will change the level of LDL and HDL level in diabetic type 2 patients compared to placebo? Researchers will compare propolis to a placebo (a look-alike substance that contains no drug) to see if propolis works to change LDL and HDL cholesterol level. Participants will: * Take propolis or a placebo, 2 times daily with given dose (1 drops/10 kg/times) every day for 2 months * Visit the sub-district health centre once every 2 weeks for checkups * Get their blood checked before and after intervention

Eligibility

Min Age: 35 YearsMax Age: 59 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether propolis (a natural substance made by bees) can help lower cholesterol levels in people with type 2 diabetes who are already on cholesterol-lowering medication. **You may be eligible if...** - You have type 2 diabetes that is reasonably well controlled (HbA1c below 7.5%) - Your BMI is between 23 and 35 - You are currently taking medication to manage your cholesterol **You may NOT be eligible if...** - You are using injectable therapies like insulin or GLP-1 receptor agonists - You have a known allergy to bee products - You are an active smoker or consume alcohol regularly - You have significant liver or kidney problems - You are pregnant or breastfeeding - You have a history of heart attack or stroke Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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