RecruitingNCT06905301

Implementation Study to Describe and Compare Retention Rate and Adherence to Adjuvant Therapy With Ribociclib With and Without Usage of Mobile Application in Patients With HR+ HER2-negative Stage II and III Breast Cancer in Real-world Practice


Sponsor

Novartis Pharmaceuticals

Enrollment

240 participants

Start Date

Jan 23, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This study is designed to evaluate the effect of using the application on the adherence of patients with luminal HER2- breast cancer (BC) stage II-III to adjuvant therapy with ribociclib in combination with an aromatase inhibitor (AI). The purpose of the app is to increase adherence to treatment by informing patients about the risks of relapse and adverse event prevention and treatment.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing whether using a mobile app alongside standard hormone-blocking treatment (ribociclib plus aromatase inhibitor) helps people with hormone-receptor-positive, HER2-negative breast cancer stay on their medications longer and adhere more consistently. **You may be eligible if...** - You have been diagnosed with stage II or III hormone-receptor-positive, HER2-negative breast cancer - You have had curative surgery for your cancer - You are 18 or older - You have been prescribed ribociclib within the past 28 days or are about to start it - You can provide written informed consent **You may NOT be eligible if...** - You are currently enrolled in another interventional clinical trial - You are receiving treatment for a different active cancer at the time of enrollment Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGRibociclib

CDK4/6 inhibitor

DRUGLetrozole

Aromatase inhibitor

DRUGAnastrozole

Aromatase inhibitor


Locations(6)

Novartis Investigative Site

Pskov, Russia, Russia

Novartis Investigative Site

Moscow, Russia

Novartis Investigative Site

Saint Petersburg, Russia

Novartis Investigative Site

Saint Petersburg, Russia

Novartis Investigative Site

Saint Petersburg, Russia

Novartis Investigative Site

Ufa, Russia

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NCT06905301


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