RecruitingNot ApplicableNCT06911632

Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension

MOMENTOUS Study (iMpact Of an Ecg ai ModEl oN The Diagnosis Of pUlmonary hypertenSion)


Sponsor

Tempus AI

Enrollment

900 participants

Start Date

Jul 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

MOMENTOUS is a multi-center, randomized study to prospectively evaluate the performance of an ECG-based AI device to predict whether participants with interstitial lung disease (ILD) are at high risk of undiagnosed pulmonary hypertension.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying ECG-based AI Device - Results Not Returned to Investigator, ECG-based AI Device - Results Returned to Investigator, and others for people with interstitial lung disease (ild) and pulmonary hypertension. The study is currently recruiting participants at 30 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICEECG-based AI Device - Results Returned to Investigator

An ECG-based AI device that predicts undiagnosed PH using data from a 12-lead ECG. Device results will be returned to the Investigators.

PROCEDUREEchocardiogram and Right Heart Catheterization

Echocardiogram- an ultrasound study of the heart and Right Heart Catheterization- a procedure to measure pressures in the heart

DEVICEECG-based AI Device - Results Not Returned to Investigator

An ECG-based AI device that predicts undiagnosed PH using data from a 12-lead ECG. Device results will not be returned to the Investigators.


Locations(37)

University of Alabama at Birmingham

Birmingham, Alabama, United States

Banner University Medical Center

Phoenix, Arizona, United States

Dignity Health - St. Joseph's Hospital and Medical Center-Norton Thoracic Institute

Phoenix, Arizona, United States

HCA Riverside Community Hospital

Riverside, California, United States

National Jewish Health

Denver, Colorado, United States

AdventHealth Orlando

Orlando, Florida, United States

Northwestern University

Chicago, Illinois, United States

University of Illinois Health

Chicago, Illinois, United States

Indiana University Health Methodist Hospital

Indianapolis, Indiana, United States

Community Health Network

Indianapolis, Indiana, United States

University of Kentucky

Lexington, Kentucky, United States

Willis Knighton Health

Bossier City, Louisiana, United States

Louisiana State University Health Shreveport

Shreveport, Louisiana, United States

Brigham and Women's Hospital

Boston, Massachusetts, United States

University of Michigan - Michigan Medicine

Ann Arbor, Michigan, United States

University of Minnesota

Minneapolis, Minnesota, United States

University of Mississippi Medical Center

Jackson, Mississippi, United States

Hannibal Regional Healthcare System

Hannibal, Missouri, United States

Mercy Hospital Springfield

Springfield, Missouri, United States

CHI Health Creighton University Medical Center - Bergan Mercy

Omaha, Nebraska, United States

Renown Regional Medical Center

Reno, Nevada, United States

University of New Mexico

Albuquerque, New Mexico, United States

University of Buffalo

Buffalo, New York, United States

Weill Cornell University Medical College

New York, New York, United States

Southeastern Research Center

Winston-Salem, North Carolina, United States

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States

University of Oklahoma

Oklahoma City, Oklahoma, United States

Thomas Jefferson University

Philadelphia, Pennsylvania, United States

Temple University of The Commonwealth System of Higher Education

Philadelphia, Pennsylvania, United States

Medical University of South Carolina

Charleston, South Carolina, United States

University of Tennessee

Knoxville, Tennessee, United States

Baylor University Medical Center

Dallas, Texas, United States

Baylor College of Medicine

Houston, Texas, United States

Houston Methodist Hospital

Houston, Texas, United States

University of Utah

Salt Lake City, Utah, United States

Virginia Commonwealth University

Richmond, Virginia, United States

West Virginia University Hospital

Morgantown, West Virginia, United States

View Full Details on ClinicalTrials.gov

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NCT06911632


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