RecruitingNot ApplicableNCT06914349

Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure

Antecolic Versus Retrocolic Gastrojejunostomy Following Pancreaticoduodenectomy: a Prospective Randomised Study


Sponsor

University of Thessaly

Enrollment

76 participants

Start Date

Mar 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy. Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded. Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two ways to connect the stomach to the small intestine during a Whipple procedure (a major surgery to remove part of the pancreas) — routing the connection in front of the colon (antecolic) versus behind it (retrocolic) — to see which leads to fewer complications such as delayed stomach emptying. **You may be eligible if...** - You are over 18 years old - You are scheduled for a Whipple procedure (pancreaticoduodenectomy) - You have signed the consent form **You may NOT be eligible if...** - You are under 18 years old - You are enrolled in another trial that could affect results - You do not wish to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREAntecolic gastrojejunostomy

Gastrojejunostomy in front of the transverse colon

PROCEDURERetrocolic gastrojejunostomy

Gastrojejunostomy through the transverse mesocolon


Locations(1)

University of Thessaly

Larissa, Greece

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NCT06914349


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